Sudhanshu Shukla |
IIT Dharwad |
Biosciences and Bioengineering |
NA |
|
Surya Pratap Singh |
IIT Dharwad |
Biosciences and Bioengineering |
NA |
|
Dr. Petety V. Balaji |
IIT Bombay |
Biosciences and Bioengineering |
Computational Biology, Bioinformatics, Glycobiology |
|
Dr. Anirban Banerjee |
IIT Bombay |
Biosciences and Bioengineering |
Bacterial Pathogenesis, Host-Pathogen Interactions, Cellular Immunity |
|
Dr. Rinti Banerjee |
IIT Bombay |
Biosciences and Bioengineering |
Nanomedicine: nanostructured biomaterials, nanotechnology platforms for drug delivery and therapeutics, pulmonary surfactants, cancer nanotechnology, liposomes and lipid self assembled nanostructures. |
|
Dr. Jayadeva Bhat |
IIT Bombay |
Biosciences and Bioengineering |
After joining IIT Bombay in 1993, research activities were initiated in three different areas of basic biology. The idea was to use Saccharomyces cerevisiae as an experimental organism to address problems pertaining to (a) Functional Genomics (b) Epigenetic Regulation of Gal Genetic Switch and (c) Human Diseases. |
|
Dr. Prasenjit Bhaumik |
IIT Bombay |
Biosciences and Bioengineering |
Understanding the structure function relationship of enzymes and biological macromolecules. Protein crystallography, Structure based antimalarial drug development, Structural enzymology |
|
Dr. Santanu Kumar Ghosh |
IIT Bombay |
Biosciences and Bioengineering |
Understanding mechanism of faithful chromosome segregation during meiotic cell division.
Functional studies of different regulatory factors involved in vegetative cell division.
Exploring 2 micron plasmid biology to study fundamental biological processes like chromatin organization and post translational protein modifications.
Epigenetic and genetic factors that influence Candida life cycle. |
|
Dr. Sandip Kaledhonkar |
IIT Bombay |
Biosciences and Bioengineering |
Structural Biology, single particle cryo-EM, cryo Electron Tomography, Time-resolved techniques |
|
Dr. Neeta Kanekar |
IIT Bombay |
Biosciences and Bioengineering |
Motor Control, Organization and execution of human movement and postural control in health and disease
Movement Neuroscience, Motor Learning, Neural Plasticity, Rehabilitation Science
Non-Invasive Brain Stimulation and Neuromodulation
Development of Rehabilitation Interventions |
|
Dr. Kiran Kondabagil |
IIT Bombay |
Biosciences and Bioengineering |
Origin and evolution of viruses
Molecular mechanisms of DNA replication, repair and packaging in giant viruses and bacteriophages
Environmental virology and virus ecology |
|
Dr. Ashutosh Kumar |
IIT Bombay |
Biosciences and Bioengineering |
Structural Biology, Biophysics,Solid and Liquid-state NMR Spectroscopy, Protein-Protein, Protein-lipid and Protein-drug interactions. |
|
Dr. Ambarish Kunwar |
IIT Bombay |
Biosciences and Bioengineering |
We use Monte-Carlo Simulations to study
Transport and force generation by motor Proteins
We use Molecular Dynamics simulations to study
Interaction of potential anti-cancer drugs with microtubules
Interaction of microtubule associated proteins (MAPs) with microtubules
Proteins involved in gonadal development and disorder
In addition, we are also working on development of various disinfection devices based on UVC and Ozone. |
|
Dr. Samir K. Maji |
IIT Bombay |
Biosciences and Bioengineering |
Studying mechanisms of protein mis-folding, aggregation and amyloid formation associated with human neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Prions.
p53 amyloids in cancer
Understanding the role of amyloid in secretory granules biogenesis in mammalian organs.
De novo design of functional amyloids for drug delivery and tissue engineering |
|
Dr. Roop Mallik |
IIT Bombay |
Biosciences and Bioengineering |
Intracellular Transport, Biophysics of Lipids and Motor Proteins, Pathogen degradation, Metabolism and Liver biology, Lipid Homeostasis |
|
Dr. Rohit Manchanda |
IIT Bombay |
Biosciences and Bioengineering |
Computational studies on synaptic transmission, electrical signalling and information processing in excitable cells and tissues. Cell types explored include smooth muscle cells and neurons of the CNS, particularly ventral striatal medium spiny neurons. Investigations have been carried out using both analytical and compartmental modelling approaches, and include studies on synaptic potentials, action potentials and underlying membrane currents. The
NEURON platform has been widely employed for the single neuron computation studies. Through our work, we attempt both to explain enigmatic electrical phenomena as well as predict the behaviour of nerve and muscle cells in response to defined sets of inputs |
|
Dr. Soumyo Mukherji |
IIT Bombay |
Biosciences and Bioengineering |
Biosensors and Bioinstrumentation: This includes physical, chemical and biological sensing systems (macro and micro) for medical / biological applications and well as telemedicine systems.
Cardiac Electrophysiology: The electrochemical events leading to and happening during acute myocardial ischemia and infarction |
|
Dr. Sreelaja Nair |
IIT Bombay |
Biosciences and Bioengineering |
The focus of our group is to understand the mechanisms driving the development of a single cell zygote into a multicellular embryo using zebrafish as our model organism. |
|
Dr. Ranjith Padinhateeri |
IIT Bombay |
Biosciences and Bioengineering |
My broad areas of interest are biophysics and soft-matter physics. I do theoretical studies to understand various physical and biological phenomena, using a variety of tools from physics including equilibrium and non-equilibrium statistical mechanics, polymer physics, and soft-matter theory. I tackle research problems using a combination of computational (numerical) and analytical methods. My specific areas of interest include: (i) Organisation of
Chromatin, (ii) Self-assembly of proteins, and (iii) Decision-making in cellular processes. |
|
Dr. Dulal Panda |
IIT Bombay |
Biosciences and Bioengineering |
Eukaryotic and prokaryotic cell division, microtubule dynamics, mitosis, cancer chemotherapy, FtsZ assembly dynamics, and FtsZ targeted antibacterial drugs and biomolecular spectroscopy |
|
Dr. Swati Patankar |
IIT Bombay |
Biosciences and Bioengineering |
Regulation of gene expression in the malaria parasite Plasmodium falciparum: transcription initiation, translation initiation, splicing
Bioinformatics analysis of P. falciparum genome sequence to study regulation of gene expression and acquisition of genetic diversity
P. falciparum tubulin as a target for anti-malarial compounds
Anti-oxidant networks in P. falciparum |
|
Dr. Rajesh Patkar |
IIT Bombay |
Biosciences and Bioengineering |
We are passionate about understanding host-pathogen interactions with a major focus on fungal molecular patho-biology, chemical effectors, host adaptability and plant biotechnology. We use both plant and animal models of fungal diseases –
Blast disease caused by the Cereal-Killer Magnaporthe oryzae
Mixed-species Invasive Candidiasis |
|
Dr. Debjani Paul |
IIT Bombay |
Biosciences and Bioengineering |
Microfluidic devices for healthcare applications
Biological physics |
|
Dr. Prashant S. Phale |
IIT Bombay |
Biosciences and Bioengineering |
Elucidation of metabolic pathways for degradation of aromatic compounds, Purification and characterization of oxygenases, Preferential utilization of aromatics compounds by Pseudomonas, Metabolic engineering of aromatic degradation pathways |
|
Dr. N. S. Punekar |
IIT Bombay |
Biosciences and Bioengineering |
Microbial Biochemistry and Molecular Enzymology (Major fields) Microbial Metabolic Regulation, Understanding Metabolism through biochemical & recombinant DNA techniques, Fungal Molecular Genetics and its Applications to Metabolic Engineering |
|
Dr. Rahul Purwar |
IIT Bombay |
Biosciences and Bioengineering |
Tumor Immunology, Cancer biomarker |
|
Dr. Shamik Sen |
IIT Bombay |
Biosciences and Bioengineering |
One of the most important breakthroughs of this post-genomic era is the finding that in addition to chemical cues, cell behaviour is equally susceptible to physical cues of the environment, including the geometry, topography and physical properties of the extracellular matrix (ECM). From embryonic development to cancer, physical forces play an important role in modulating cell processes including cell sorting, proliferation, differentiation and angiogenesis. The broad goal of my research plan will be to understand how physical forces influence cell and matrix mechanics through a combination of experimental and computational techniques. To contribute to this understanding, I will explore how development and cancer progression are regulated by the physical crosstalk between the cell cytoskeleton and the ECM. |
|
Dr. Rohit Srivastava |
IIT Bombay |
Biosciences and Bioengineering |
Fluorescent Biosensors, Nanoengineered Sensors, Controlled Release, Layer-by-Layer Self-Assembly, BioMEMS, Photothermal therapy for breast cancer |
|
Dr. Sanjeeva Srivastava |
IIT Bombay |
Biosciences and Bioengineering |
Proteomics describes the study and characterization of complete set of proteins present in a cell, organ or organism at a given time. My laboratory is using high throughput proteomic techniques such as two-dimensional difference in gel electrophoresis, mass spectrometry and protein microarray etc. for biomarker discovery in cancer & tropical diseases of India such as malaria, to study protein-protein interactions and drug target discovery. Information obtained from research program is also used for in silico studies and computing models to enhance our understanding in systems approach.
|
|
Dr. G. Subrahmanyam |
IIT Bombay |
Biosciences and Bioengineering |
The complexity and fine tuning of T cell and mast cell activation signaling cascades are the focus of the lab. Our studies have shown that a type II PtdIns 4-kinase activity is associated with CD3, CD4, CD7 and CD28 receptors in T cells and with FcRI in mast cells. These studies suggest that type II PtdIns 4-kinases may generate a threshold of signals at plasma membrane that may regulate immune synapse formation, T cell adhesion and infiltration
and inflammatory responses. Type II PtdIns 4-kinases have also been shown to play a role in microbial pathogenicity and neuronal signaling. Understanding of type II PtdIns 4-kinases function and its regulators may help in development of rational drug design for immunomodulators and possibly in cancer metastasis.
The other projects that have been initiated recently in our lab are on stress signaling mechanisms in a marine algae Dunaliella salina, and Pheodactylum tricornutum. D. salina responds to different stress conditions by accumulating large quantities of carotenoids and the focus of the lab is to dissect out these signaling pathways and generate stable mutants in these pathways. P.tricornutum under stress conditions accumulates large quantities of triacylglycerols and regulation of triacylglycerol biosynthesis is another line of research in the lab |
|
Dr. Prakriti Tayalia |
IIT Bombay |
Biosciences and Bioengineering |
Our lab has progressively been developing various kinds of material based systems for replicating and understanding in vivo physiological phenomena. With that aim, we are working with three-dimensional (3D) cell culture platforms both for delivery of bioactive molecules as well as recruitment or culture of cells, which can broadly be used for the following applications.
(1) Material-based gene delivery: We have an in house expertise of making lentiviral particles for different kinds of genetic modification of cells. We have tried a variety of plasmids and have used different material platforms for delivery of these particles to cells in vitro as well as in vivo. We can transduce different cells using various direct or material based approaches to manipulate cells ex vivo or allow in situ (or in vivo) genetic modification of cells respectively. We are using this platform for immunotherapy and tissue regeneration applications.
(2) Porous cryogel scaffolds for 3D cell culture: We have also developed a macroporous hydrogel platform for immunotherapy and spheroid formation.
Immunotherapy: These porous matrices can be loaded with programming factors such as growth factors (or chemokines) and gene delivery vectors, which can be temporally controlled and used to recruit and manipulate host cells upon
in vivo implantation. This approach when used in a more cell specific manner with immune cellshas applications in immunotherapy.
Tissue regeneration: Our cryogel matrices are also being developed as an off the shelf degradable macroporous matrix system for full thickness skin regeneration. We plan to develop this system as a substitute for the currently used decellularized cadaveric skin, autografts or other expensive allogeneic cell based or acellular matrices imported in the Indian market.
Spheroid formation: By modulating the composition of these porous matrices, we can grow clusters or spheroids of various kinds of cells. These 3D cell culture platforms can be used (1) to understand underlying cellular mechanisms in normal and pathological conditions and (2) for drug screening applications by exploring cell-cell and cell-ECM interactions, influence of immune cells on tumor cells and vice versa.
Better understanding of cellular mechanisms in various applications will enable these material based systems developed in our group to be taken forward for some real clinical applications. |
|
Dr. Hari Varma |
IIT Bombay |
Biosciences and Bioengineering |
Developing novel optical tools for medical imaging applications.
Laser speckle contrast imaging and diffuse correlation spectroscopy/tomography for blood flow measurements.
Inverse problems in medical imaging: Theoretical and computational aspects of diffuse optical tomography. |
|
Amal Kanti Bera |
IIT Madras |
Biotechnology |
Structure function relationship of ion channels
Gap Junction Channel
GABAA Receptor Channel
Voltage Dependent Anion Channel of Mitochondria
Potassium Channel and Acid Sensing Ion Channel
Neuronal diseases associated with ion channels and receptors malfunctionin |
|
Anju Chadha |
IIT Madras |
Biotechnology |
Asymmetric Synthesis using enzymes
Biocatalysis and Enzyme Mechanisms
Bionanotechnology
Biosensors
Chirotechnology
Enzymes in Organic Synthesis
Green Chemistry |
|
Athi N. Naganathan |
IIT Madras |
Biotechnology |
Experimental Characterization of Protein Conformational Behavior
Modeling and Predicting Folding Landscapes using Statistical Models
Understanding Protein Folding and Dynamics through Coarse-Grained and All-Atom Molecular Simulations
Multi-Scale Exploration of Protein Conformational Ensembles |
|
R Baskar |
IIT Madras |
Biotechnology |
Mechanisms of pattern formation in cellular slime molds.
Estimating spontaneous mutation rates during plant development. |
|
T S Chandra |
IIT Madras |
Biotechnology |
Biotechnology for food,feed and fuel Riboflavin enriched animal feed supplement , rib gene expression ,lipase and membrane fluidity changes by fluorescent probes in ascomycetes fungi. Nutraceuticals , phenolic antioxidant activity ,wound healing and anti-glycaemic effects in millet diet.
Molecular Microbial Diversity in compost ,vermicompost of sugar industry wastes (pressmud, bagasse ,trash etc) Low temperature biogasification , psychrotrophic microbes and cold-tolerant industrial enzymes (xylanases , cellulose , B-galactosidase etc). |
|
Mukesh Doble |
IIT Madras |
Biotechnology |
1. Drug Design and QSAR for Anti-inflammatory, Antimicrobial, Antidiabetic, Anti-TB agents
Enzyme-Ligand Binding studies
Synergy of natural products and synthetic drugs
Modelling of drug delivery systems (polymer and drug- Interactions)
2. Polymers in Medical Applications
Orthopedic implants, Analysis of arterial explants, urinary stents
Bacterial adhesion/Biofilm, Surface modifications
3. Biodegradation/Biofouling of Polymers
Marine and soil organism mediated
Biosurfactants
4. Scale-up of Chemical processes – (Rubber Chemicals, Plastics, Specialty Chemicals, Pharmaceuticals and Paints).
Bioreactor design
Reaction mechanism studies of homogeneous, heterogeneous and enzyme catalysed reactions
5. Systems modelling (EEG and disease classification, pathway of Parkinson disease)
6. Statistical process control, Biostatistics and Six-Sigma. |
|
A Gopala Krishna |
IIT Madras |
Biotechnology |
G-Protein Coupled Receptor (GPCR) mediated signal transduction pathways
Mechanism of G protein activation
Membrane protein biochemistry
Protein structure-function
Protein folding |
|
Guhan Jayaraman |
IIT Madras |
Biotechnology |
Metabolic engineering and systems biology
Recombinant protein production
Bioprocess monitoring and control
Chromatographic bioseparation processes |
|
M Hamsa Priya |
IIT Madras |
Biotechnology |
Bio-molecular simulations
Design of drug delivery carriers
Multi-scale modeling
Peptide self assembly for therapeutics
Protein solubility and aggregation |
|
Himanshu Sinha |
IIT Madras |
Biotechnology |
Quantitative and population genetics – genetical and environmental variation
Genetic and regulatory networks in yeast
Systems biology
Large scale human transcriptome and variation data analysis |
|
K Chandraraj |
IIT Madras |
Biotechnology |
BioEthanol Production
Ethanol-Blended-Petrol (EBP) has E3 benefits viz. Economic, Environmental and Energy. India implemented 5% EBP in 2002, proposed to increase to 10% EBP in 2009 and further increase to 20% EBP by 2017. Molasses based ethanol is the only source for ethanol in India. Decline in sugar production in 2008-09 severely affected molasses-ethanol production. Current ethanol production from molasses could meet 5% EBP. To achieve higher ethanol blending other sources are need for ethanol production. Non-food plant sources such as cellulosic plant biomass and sorghum juice are the promising sources to produce bioethanol for EBP program. Our research is focused on process development for economical production of fuel-ethanol from crop residues and sorghum juice.
Functional Oligosaccharides (FOS)
FOS are oligosaccharides with specific physiological functions beyond the basic nutrition. Because of the increasing health problems, caused by stress at work, environmental pollution and unbalanced food in recent days, there have been concerns over functional foods to maintain good health. FOS have lower sweetness than sucrose, high viscosity, low calorific value, resist hydrolysis in gastrointestinal tract and stimulate the proliferation of probiotics, Bifidobacterium sp. and Lactobacillus sp. We are developing economic process for FOS production from plant biomass using enzymes.
Molecular Bioremediation of Cr(VI)
Environmental pollution due to industrialization is the major concern. Heavy metal pollution is a serious issue and chromium is one of the highly toxic metal pollutants. Chromium is emitted to environment from several industrial processes including nuclear power generation. Cr at hexavalent oxidation state is highly toxic to living systems. An efficient way of preventing Cr(VI) pollution is its reduction to Cr(III) which is much less toxic. Biocatalysts such as bacteria and enzymes have the capacity to detoxify Cr(VI) by conversion to Cr(III). Molecular techniques can be employed to improve the bioremediation potential of biocatalysts for application in actual polluted sites. Current research in our lab involves isolation and engineering of enzymes for transformation of Cr(VI) to Cr(III). |
|
Karthik Raman |
IIT Madras |
Biotechnology |
Computational Approaches to Understand and Manipulate Biological Networks
Biological Big Data Analysis
High-performance Computing for Systems Biology
In silico metabolic engineering
Theoretical investigations into biological networks |
|
D Karunagaran |
IIT Madras |
Biotechnology |
Mechanisms of Apoptosis activated by anticancer agents
Signaling by growth factors
NF-kappa B signaling
|
|
V Kesavan |
IIT Madras |
Biotechnology |
Design and synthesis of novel privileged chiral ligands for asymmetric catalysis
Design novel non-hydroxamate inhibitors against HDAC to treat cancer
Peptide mini-vectors for delivery of siRNAs |
|
Madhulika Dixit |
IIT Madras |
Biotechnology |
The primary objective of my research team is to elucidate molecular and cellular mechanisms of normal and aberrant function of blood vessels under physiological and patho-physiological conditions respectively. The key areas
we focus on are endothelial dysfunction, atherosclerosis and edema. In order to obtain a holistic picture on these issues we subscribe to the following approaches:
High through put screening for identification of changes in gene expression from clinical samples.
In vitro tissue culture experiments to identify signaling intermediates altered under pathological settings. For this we employ primary cultures of vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs).
Validation of in vitro data through in vivo animal experiments.
Use of viral vector based gene delivery systems to rectify the faulty functioning of the signaling intermediates. |
|
S Mahalingam |
IIT Madras |
Biotechnology |
1. Molecular pathogenesis of HIV/AIDS
Virus-host interaction, mechanism of HIV mediated cell cycle arrest, and role of integrase during very early steps in viral infection.
2. Regulation of nucleo-cytoplasmic transport proteins
Identification and characterization of protein nuclear and nucleolar transport using both cellular and viral proteins.
3. Cancer biology
a.Understanding the cross talk between tumor suppressors and activators of cell proliferation, mechanism of Ras associated tumor suppressor mediated cell growth control.
b.Nucleolus on cell proliferation and cancer: Nucleolus play a very important role in rRNA production, processing, and ribosome biogenesis. Understanding the role nucleolar proteins in cell proliferation and tumor development is critical.
c.Cancer Genomics: Cancer specific biomarkers for early detection and drug target identification, Development of cancer Genome database specific to Indian population
d.Genomics of pancreatic cancer and childhood leukemia. |
|
N Manoj |
IIT Madras |
Biotechnology |
Structural biochemistry of hydrolases
Protein structure and function
Computational molecular evolution
Bioinformatics
|
|
M Michael Gromiha |
IIT Madras |
Biotechnology |
Discrimination of membrane proteins based on structure and function
• Prediction of membrane spanning segments in alpha-helical and beta-barrel membrane proteins
• Recognition of protein folds
• Prediction of secondary and tertiary structures in globular proteins
• Conformational stability of proteins and nucleic acids
• Identification of important residues for protein stability and function
• Extreme stability of thermophilic proteins |
|
R Murugan |
IIT Madras |
Biotechnology |
Random walks and jumps in Biology
Kinetics of DNA-protein & DNA-DNA interactions
Biochemical & Genetic Networks – Systems Biology |
|
Nirav P Bhatt |
IIT Madras |
Biotechnology |
Modelling, Control, and Optimization of Biological and Disease Networks from Multi-sensor and Multi-scale Data
Integrated (Bio-)process Manufacturing
Bioprocess Control and Process Analytical Technology
Learning and Control of Complex Man-made Networks from Data |
|
Nitish R Mahapatra |
IIT Madras |
Biotechnology |
Cardiovascular diseases (coronary heart disease, heart failure, stroke etc.) affect a large section of the adult population and are the leading causes of morbidity and mortality in many countries including India. Recent studies have documented that although the mortality associated with cardiovascular diseases are declining in the developed countries including Western Europe and North America, the burden of cardiovascular diseases continues to rise in the developing countries including India. Notably, South Asians have a greater prevalence of cardiovascular risk factors than the rest of the World, and India itself is estimated to have more than half of the World’s heart disease patients at present. These diseases not only cause enormous loss of human lives, but also lead to huge health care cost, tremendous economic and social burden, declining national productivity and quality of life.
The determinants of cardiovascular diseases are multi-factorial, complex and often interrelated. We are interested to understand the molecular and genetic bases of hypertension (elevated arterial blood pressure) because it is the chief risk factor for cardiovascular diseases. Despite extensive research over the past couple of decades, the pathogenesis of hypertension is only partially understood. Besides environmental factors (such as stress, inadequate physical activity, smoking/tobacco use and unhealthy diet that includes higher dietary fats/higher sodium/lower fruits and vegetables), strong influences of genes have been reported. Moreover, hypertension may be associated with and complicated by dyslipidemia (elevated levels of LDL-cholesterol and triglycerides and reduced level of HDL-cholesterol in the circulation), a major risk factor for cardiovascular diseases. In addition, diabetes mellitus is another major risk factor for cardiovascular diseases. Indeed, more than 65% of people with diabetes mellitus die of some form of heart disease/stroke and heart disease death rates in adults with diabetes are at least two times higher as compared to those without diabetes. Therefore, we are also interested to unravel the genetic and molecular mechanisms that govern the pathogenesis of lipid disorder and type 2 diabetes.
Our experimental approach involves identification, transcriptional and post-transcriptional regulation of the candidate/susceptibility genes for hypertension and related cardiovascular disease states. We also study the roles of
translated protein products of the candidate genes in disease pathogenesis. Additionally, we work on discovering naturally-occurring functional genetic variants (single nucleotide polymorphisms and haplotypes) that may act as risk factors for development of cardiovascular diseases. We investigate at the cellular level (employing cultured cell lines), utilize animal models (genetically modified rodents) and human subjects (cases versus controls) for our various studies. Results from these studies are likely to shed light on the molecular mechanisms and ultimately help to develop diagnostic and therapeutic strategies for management of the cardiovascular diseases. |
|
Rama S Verma |
IIT Madras |
Biotechnology |
1- Stem cell proliferation related studies
A- Role of Osteoblasts in Stem Cell Proliferation
Hematopoiesis is an exquisitely regulated physiological process, which results in the appropriate production of blood cells throughout life. Over the past four decades our understanding of the cellular and molecular basis of hematopoietic regulation has become quite sophisticated. Several hematopoietic growth factor polypeptide hormones have been identified through molecular cloning, which play a key role in this process. In many respect, our current dynamic model of hematopoietic is the leading paradigm in molecular histology. It has established a framework to apply to cell differentiation and renewal in diverse tissue, including liver, skin and intestinal epithelium. Despite these advances, the most important details of the cellular and molecular regulation of stem cell self- renewal and differentiation remain elusive. We are currently addressing these issues through the following:
Role of permissive and inductive microenvironment in bone marrow in context to proliferation of stem cell
Role of osteoblast in the proliferation of stem cell
B- Stem Cell and its Regenerative Potential
2- Construction of Novel & New fusion Toxin (Immunotoxins)
Recombinant immunotoxins are antibody-toxin chimeric molecules that kill cancer cells via binding to a surface antigen, internalization and delivery of the toxin moiety to the cell cytosol. In the cytosol, toxins catalytically inhibit a critical cell function and cause cell death. The antibody portion of the chimera targets antigens that are expressed preferentially on the surface of cancer cells. Truncated versions of either diphtheria toxin (DT) or Pseudomonas exotoxin (PE) can be used to construct fusions with cDNAs encoding antibody fragments or cell- binding ligands. Presently, in our lab we have designed several novel constrct which are truncated version of known immunotoxins and novel humanized toxin utilizing the pre-apoptoctic segment of human origin to combat the problems associates with the immnogenicity of the toxin fragment and the non-targeted toxicity noted while treating certain cancers.
3- Cloning & Expression of Therapeutic Protein that have Clinical Importance
4- Development of MAB against EpCAM for Targeting Retinoblastoma with Nanoparticle
5- Biochemical and Molecular Characterization of membrane Protein Receptor) Presently our interest is in “Identification and Purification of Methotrexate Binding protein from the T Lymphocytes
6- Nanotechnology Using synthetic biodegradable micro-molecules and biodegradable biopolymer as scaffold for stem cell differentiation into cardiac tissue for heart injury repair.
|
|
Sanjib Senapati |
IIT Madras |
Biotechnology |
* PROTEIN DYNAMICS
We focus on understanding the relationship between protein structure, function, and dynamics. Research is focused into two major sub-groups: 1) molecular modeling of enzyme-substrate / enzyme-inhibitor interactions and 2) structure-based drug discovery. Studies are performed using computer simulation methods ranging from molecular dynamics simulations, Monte Carlo simulations, Brownian dynamics simulations, and protein-ligand docking. General properties that we address include change in protein structure and dynamics upon binding inhibitors and with mutations, ligand binding strength and specificity, and bound water structure.
* GREEN CHEMISTRY
Ionic liquids and super critical CO2 have been identified as promising green solvents for biotransformation, enzyme catalysis and long-term preservation of biomolecules. Our objective is to elucidate molecular level interactions between biomolecules and ionic liquids, modulated kinetics of protein folding and increased solubilization & enhanced extraction of proteins and other hydrophilic substances in water-in-CO2 reverse micelles, etc.
* NANO CLUSTERS
We, perform first-principle quantum mechanical calculations of gold, silver and gold-silver binary clusters to understand their electronic structures, magic number, vibrational spectra, adsorption behavior, response to electric
field, catalysis, etc.
* In-vitro STUDIES
While rationalizing experimental behavior of biomolecules using molecular dynamics simulation remain our forte, we have moved on to use MD as a central engine of experimental research by validating our findings from computational studies using various spectroscopic & calorimetric techniques. With leads from our computational data we perform inhibitor synthesis, enzymatic assays and drug design in our laboratory. |
|
Sathyanarayana N Gummadi |
IIT Madras |
Biotechnology |
Microbial and Enzymatic approaches for the production of industrial metabolites
Unravelling the mechanism and biological significance of flippases and scramblases on phospholipid translocation across biological membranes
Production of biomaterials and nanoparticles various industrial and medical applications |
|
SHANTANU PRADHAN |
IIT Madras |
Biotechnology |
Biomaterials, Hydrogels, and Synthetic Scaffolds
In vitro Modeling of Cellular Microenvironments
Engineering Cancer, Metastasis, and Tumor Angiogenesis
Microfluidic On-chip Technologies
​Biofabrication Technologies |
|
Smita Srivastava |
IIT Madras |
Biotechnology |
Bioprocess development and optimization for large scale in vitro production of high-value phytochemicals and phytoremediation. |
|
V Srinivasa Chakravarthy |
IIT Madras |
Biotechnology |
Computational Neuroscience
Modeling Basal Ganglia to understand Parkinson’s disease
Modeling neuro-glio-vascular interactions
Modeling visuomotor dynamics of copying
Modeling the development of topographic maps in the brain
Computational Cardiology
Modeling Cardiac memory
Role of chaotic vasomotion in microvascular dynamics
Computational electrophysiology
Biomedical Engineering
Extracting Gastric Motility information from finger Photoplethysmography (PPG)
Pattern Recognition
Online handwritten Character Recognition in Indian Languages |
|
K Subramaniam |
IIT Madras |
Biotechnology |
Most of our tissues undergo constant wear and tear. A group of cells, known as the adult stem cells, continuously generate new cells that help our tissues regenerate and repair. In a population of stem cells, while some undergo cell division to self-renew their population, others differentiate to produce the specialized cells that make up a particular tissue. Maintenance of a balance between self-renewal and differentiation is crucial – bias towards self-renewal can cause cancer, and bias towards differentiation will result in the loss of stem cells. My laboratory investigates how this balance is achieved in the case of germline stem cells.
Germline stem cells (GSCs) serve as an experimentally-convenient model to study adult stem cell systems. Like the other types of adult stem cells, GSCs are capable of self-renewal and differentiation; they can either replenish
themselves through mitosis, or undergo meiotic differentiation to produce the gametes egg and sperm. However, unlike the other adult stem cell populations, GSCs are readily available in genetically-tractable model organisms, such as the free-living nematode Caenorhabditis elegans. Therefore, we have chosen C. elegans GSCs as an adult stem cell model and investigate how these cells choose between mitotic and meiotic fates. This approach allows us to
employ the various genetic and biochemical strategies available for the C. elegans animal model to studying adult stem cells. Since the process of mitotic and meiotic fate decisions have been conserved in evolution, we hope our discoveries will be informative to similar studies in other species as well.
Currently, our work centres on the RNA-binding protein PUF-8, which belongs to the well-conserved PUF family of RNA regulators. PUF proteins control stem cell proliferation in diverse biological contexts in a number of species. Intriguingly, our results reveal that PUF-8 is essential for both proliferation and differentiation. We find that PUF-8 regulates diverse cellular processes to control germ cell decisions; it accomplishes this by both positively and negatively regulating the translation of certain mRNAs in the germline. In a genetic screen, we isolated new mutant alleles in a number of genes that genetically interact with PUF-8. Presently, we are investigating the biochemical basis of these genetic interactions, to understand how PUF-8 controls self-renewal and differentiation decisions in the germline. |
|
G K Suraishkumar |
IIT Madras |
Biotechnology |
In the Biotechnology domain:
We work in the general area of better understanding and manipulation of biological systems. We have chosen to contribute to the area of reactive species (RS), which we believe are the molecular mediators of cellular stress, and
we work to better understand RS effects on biological systems with a view to manipulate them toward desirable ends. The current applications are
Cancer treatment and management
Nanoparticle toxicology
Our earlier work in the above area has resulted in contributions to improve
Bioreactor operation
Biofuels from microalgae
We have made fundamental, novel contributions in the above areas.
In addition, we have made the following contributions
Devised a generalized strategy for oxygen supply to bioreactors without aeration (LPOS)
Developed bio-sorbents for toxic trace metal removal
Developed a NIR based soft probe that has been employed in Biocon Industries
In the learning facilitation domain:
I have a deep interest in the learning process, and I do a lot of experiments on the same. Significant contributions have been made in the area – please see the disseminated information (journal articles, books, MOOCs, etc.) in the other pages. |
|
Suresh Rayala |
IIT Madras |
Biotechnology |
Cancer Biology – Developing small molecules/peptides targeting novel oncogenes, establishing the molecular mechanism of action of new drugs – using CRISPR/Cas9 screens, studying mechanisms of therapy resistance, and developing pre-clinical models of tumor progression including xenografts (patient derived explant [PDeX] and patient derived Xenograft [PDX]) models.
Expertise in generating Monoclonal and Polyclonal antibodies for diagnostic applications |
|
Vani Janakiraman |
IIT Madras |
Biotechnology |
Tuberculosis (TB) is a disease caused by the bacteria Mycobacterium tuberculosis.Tuberculosis claims about 2 million lives annuallyand is the leading cause of death worldwide due to a single bacterial agent. The situation is particularly alarming in several developing countries including India, with India accounting for 30% of the global burden of tuberculosis. In addition, the emergence and spread of drug resistant strains (that are resistant to most antibiotics currently in use)and thesynergistic association of this disease with AIDS, are posing major challenges for tuberculosis control. For these reasons, world health organisation (WHO) has announced tuberculosis as a
‘global emergency’.
Mycobacteria are intra-cellular pathogens that have developed specific mechanisms to invade and survive within their host. The host-pathogen interplay is complex. Upon infection with M. tuberculosis, either active active tuberculosis disease can develop or the bacteria can remain dormant causing latent tuberculosis. In latently infected individuals, the infection may reactivate and cause active tuberculosis. The reactivation risk is higher when confronted by immune suppression, for example, upon co-infection with HIV.
tuberculosis poses extraordinaryintellectual and medical challenge, as ~40% of its genes are of unknownfunction. The entire genome of M. tuberculosis, comprising approximately 3924 open reading frames, has been sequenced. Examining the mechanisms by which M. tuberculosis activates or evades the host immune responses is a key to developing a greater understanding of the pathology of tuberculosis.
Our lab works in the interface of Microbiology and Immunology. Our research interests focus on understanding the host-pathogen interaction in tuberculosis at molecular level and gaining insights into the immune surveillance mechanisms of the host during infection, with an ultimate aim of designing better diagnosis and intervention strategies for tuberculosis.
We are specifically interested
(i) Identifying and characterizing novel genes that contribute to the virulence and pathogenicity of M.tuberculosis
(ii) Understanding the role of novel innate immune receptors in modulating immune responses during tuberculosis
(iii) Deciphering bacterial communication in Mycobacteria: Communication in lower organisms is very fascinating. They do so for multiple reasons for example, for virulence enhancement and for acquiring antibiotic resistance. We are trying to unravel the cell to cell communication machinery in Mycobacteria. |
|
Vignesh Muthuvijayan |
IIT Madras |
Biotechnology |
Designing multifunctional bioactive scaffolds for tissue regeneration
Developing controlled drug delivery systems
Engineering surfaces for long term patency |
|
Amitabha Bandyopadhyay |
IIT Kanpur |
Biological Sciences & Bioengineering |
Skeletal development and differentiation. |
|
Appu K. Singh |
IIT Kanpur |
Biological Sciences & Bioengineering |
Ion-channels, calcium signaling, Cryo-electron microscopy, X-ray crystallography, electrophysiology, fluorescence spectroscopy |
|
Arjun Ramakrishnan |
IIT Kanpur |
Biological Sciences & Bioengineering |
Systems neuroscience, decision making, mental health, electrophysiology, EEG, cognition |
|
Arun Kumar Shukla |
IIT Kanpur |
Biological Sciences & Bioengineering |
Structural biology; cellular signaling; combinatorial biology |
|
Ashok Kumar |
IIT Kanpur |
Biological Sciences & Bioengineering |
Downstream processing; affinity interactions and cell separations; nanotechnology; biomaterials; tissue engineering |
|
Ashwani Kumar Thakur |
IIT Kanpur |
Biological Sciences & Bioengineering |
Protein aggregation in diseases and therapeutic design; self assembly of proteins; biopharmaceuticals; neurodegenerative disorders |
|
Bushra Ateeq |
IIT Kanpur |
Biological Sciences & Bioengineering |
Molecular oncology and cancer therapeutics |
|
Dhirendra S. Katti |
IIT Kanpur |
Biological Sciences & Bioengineering |
Tissue engineering; controlled drug delivery system; biomaterials |
|
Dibyendu K. Das |
IIT Kanpur |
Biological Sciences & Bioengineering |
Single molecule imaging; optical tweezers; virology and immunology |
|
Ganesh, S |
IIT Kanpur |
Biological Sciences & Bioengineering |
Neurobiology of disorders, stress biology, and human genetics |
|
Hamim Zafar(jointly with CSE) |
IIT Kanpur |
Biological Sciences & Bioengineering |
Computational biology; probabilistic modeling; single-cell biology; evolution and cancer |
|
Jayandharan G. Rao |
IIT Kanpur |
Biological Sciences & Bioengineering |
Gene therapy: Neuro-ophthalmic disorders; Blood disorders; Cancer gene therapy; Human molecular genetics |
|
Jonaki Sen |
IIT Kanpur |
Biological Sciences & Bioengineering |
Vertebrate neuronal development |
|
Mainak Das |
IIT Kanpur |
Biological Sciences & Bioengineering |
Materials |
|
Nitin Gupta |
IIT Kanpur |
Biological Sciences & Bioengineering |
Neuroscience, insect olfaction and behavior, digital interventions for human mental health |
|
Nitin Mohan |
IIT Kanpur |
Biological Sciences & Bioengineering |
Optical engineering; super-resolution microscopy; applications in neurodegenerative disorders, lysosomal storage disease & cancer |
|
Pradip Sinha |
IIT Kanpur |
Biological Sciences & Bioengineering |
Drosophila cancer genetics and therapeutics |
|
Sai Prasad Pydi |
IIT Kanpur |
Biological Sciences & Bioengineering |
Diabetes, Obesity, NAFLD, Immunometabolism, GPCRs, Cell Signaling |
|
Sankararamakrishnan, R. |
IIT Kanpur |
Biological Sciences & Bioengineering |
Modeling and simulation of biomolecules; bioinformatics |
|
Santosh K. Misra |
IIT Kanpur |
Biological Sciences & Bioengineering |
Biosensors, personalized medicine, bubble therapy, 3D-printed biomedical devices, carbon composites, drug delivery systems, nanocomposites. |
|
Saravanan Matheshwaran |
IIT Kanpur |
Biological Sciences & Bioengineering |
Chromatin dynamics and DNA repair; microbiology |
|
D. Sundar |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Bioinformatics and Computational Biology; Genome engineering, Big data Genomics; Biological activity of natural drugs |
|
Shaikh Z. Ahammad |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Water and Wastewater Treatment -Physico-chemical and Biological, Anaerobic Wastewater Treatment; Bioremediation of Emerging Pollutants; Antibiotic Resistance in the Environment; Bioreactor Design |
|
Lucinda Elizabeth Doyle |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Electrochemically-active microorganisms |
|
Ravikrishnan Elangovan |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Single Molecule Biophysics; fluorescence spectroscops; molecular motors; skeletal muscle mechanics |
|
Ishaan Gupta |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Single-cell gene expression technology development to study heterogeneity, end-to-end development of novel transcriptomic assays to measure biological phenomena with high precision and accuracy. |
|
Rohan Jain |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Biological wastewater treatment, Adsorption, resource recovery, scale-up, Critical metal recovery, bio-ligands, scale-up |
|
Ritu Kulshreshtha |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
MicroRNAs in Cancer Biology; Cancer/Disease Biomarkers; Tumoral Hypoxia Research; RNAi technology |
|
Prashant Mishra |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Protein Engineering; Non aqueous Enzymology, Nanoparticles based drug delivery; Protein based nanodevices |
|
Ashish Misra |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Metabolic analyses and engineering |
|
K.J. Mukherjee |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Bioprocess optimization and scale up. Primary interest is in designing host platforms for over-expressing metabolites and recombinant proteins and linking then with bioprocess strategies for overproduction. The work involves metabolic engineering of host pathways and rational design using structured modelling approaches |
|
Atul Narang |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Systems Biology of Microbial Gene Regulation |
|
Sunil Nath |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Bioseparation; Mechanism and Thermodynamics of ATP-based Molecular Machines; Molecular Systems Biology/Engineering |
|
T.R. Sreekrishnan |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Waste Engineering and Environmental Biotechnology-Development; modelling and optimization of aerobic and anaerobic biological treatment processes for high strength and toxic industrial waste streams; Biodegradation of xenobiotic compounds; Production of biodegradable polymers; Development of biosensors for monitoring environmental pollutants |
|
Shilpi Sharma |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Plant-microbe interaction; microbial diversity; microbial dynamics in waste water treatments and rhizospheres; effect of various biotic and abiotic factors on structure and function of microbial communities in terrestrial ecosystems especially targeting genes involved in nitrogen cycling |
|
Preeti Srivastava |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Chromosome maintenance in bacteria; Plasmid replication and segregation in bacteria; Biodesulfurization of petroleum fractions |
|
Madhuresh Sumit |
IIT Delhi |
BIOCHEMICAL ENGINEERING AND BIOTECHNOLOGY |
Integrating computational and experimental systems biology to understand and manipulate cell responses; Multi-scale modeling of non-linear physiological systems and bio-processing units; Application of integrated systems approach towards process optimization; Miniaturization of bioprocessing for personalized medicines. |
|
Dr. Aravind Kumar Rengan |
IIT HYDREBAD |
BIOMED |
Nanomedicine, Cancer Nanotechnology, Photothermal Therapy, AMR, Biomaterials, Drug Delivery, Proton Beam Therapy |
|
Dr. Avinash Eranki |
IIT HYDREBAD |
BIOMED |
Therapeutic Ultrasound (HIFU/FUS), Diagnostic Ultrasound, Ultrasound-based Drug Delivery, Acoustics, Cancer Therapy, Rehabilitation & Sports Medicine, Point-of-Care Ultrasound, Translational (Bench-to-Bedside) Device Development, Clinical Trials |
|
Dr. Falguni Pati |
IIT HYDREBAD |
BIOMED |
Biofabrication; Tissue Engineering; Regenerative Medicine; In vitro tissue/organ/tumor models |
|
Dr. Harikrishnan Narayanan Unni |
IIT HYDREBAD |
BIOMED |
Micro and Nano Scale flows and particle/cell interactions, Biomolecule transport and Mesoscale Properties, Dissipative Particle Dynamics (DPD) simulation, Micro-Nano Fabrication of Lab-on-a Chip devices and Biosensors. |
|
Dr. Jyotsnendu Giri |
IIT HYDREBAD |
BIOMED |
Nanomedicine, Regenerative Medicine, Oral Care, Diagnostic and Therapeutic, Drug and Biomolecules (protein,siRNA) delivery, Novel Biomaterials, Clinical Application of Stem Cells and iPS cells. |
|
Dr. Kousik Sarathy Sridharan |
IIT HYDREBAD |
BIOMED |
Neuromodulation, Neuroimaging, Intra-operative neuromonitoring, Healthcare data analytics |
|
Dr. Mohd Suhail Rizvi |
IIT HYDREBAD |
BIOMED |
Biomechanics, Biophysics, Systems Biology. |
|
Dr. Mohan Raghavan |
IIT HYDREBAD |
BIOMED |
Virtual Physiology; Computational Neuroscience; Neuromechanics; Motor Systems Simulations. |
|
Dr. Renu John |
IIT HYDREBAD |
BIOMED |
Novel non-invasive bio-imaging techniques, Coherence imaging and microscopy techniques, Quantitative phase Microscopy, Molecular contrast agents and Targeted molecular imaging, Biosensing and Point of care Devices, Nanoparticles, Targeted drug delivery and Biophotonics applications. |
|
Dr. Subha Narayan Rath |
IIT HYDREBAD |
BIOMED |
In vitro stem cell-biomaterial interactions using micropatterning and nanofibers, In vivo like bioreactor use for tissue development, Molecular analysis of angiogenesis, osteogenesis, and diabetic cell therapy, Application of 3D-cell printing for vascularized and osteo-chondral tissues. |
|
Srinivas Kiran Ambatipudi |
IIT ROORKEE |
BIOMED |
Application of proteomics in elucidate the role of milk proteins in the pathophysiology of animal disease, Investigate the role of salivary proteins in breast cancer progression, |
|
Harsh Chauhan |
IIT ROORKEE |
BIOMED |
Plant Molecular Biology, Biotechnology, Functional Genomics, Response to Biotic and Abiotic Stresses, Transgenic Crops, Nutrigenomics, |
|
Bijan Choudhury |
IIT ROORKEE |
BIOMED |
Biochemical engineering, Biotransformation, Enzyme technology, metabolic modelling, bioenergy, |
|
Kaushik Ghosh |
IIT ROORKEE |
BIOMED |
Inorganic Biochemistry, Catalysis, Organometallic Chemistry, Coordination chemistry, Metal complexes and their interactions with DNA and proteins, Inorganic Chemistry, Bioinorganic and organometallic chemistry, |
|
Sanjoy Ghosh |
IIT ROORKEE |
BIOMED |
Biochemical Engineering/Bioprocess Engineering, Biofuel production; Enzyme production; Reactor design; Modeling, simulation and scaling-up, Biofuel Production, Bioethanol production; Biodiesel production; Fractional hydrolysis; Microalgae cultivation, Enzyme Production, Phytase, Laccase and Cellulase production; Solid state fermentation, Reactor Design, New bioprocess equipments such as fractional hydrolysis column, SSF bioreactor, Photo-bioreactor, Modeling, Simulation and Scaling-up, Mathematical modeling, process simulation and scaling-up, |
|
Saugata Hazra |
IIT ROORKEE |
BIOMED |
Structural Biology, Protein crystallography, Structure based drug development, Enzymology, Enzyme kinetics, Biophysical & biochemical studies, Structure-function relationship, Computational Biology, MD simulation, Virtual screening, Macromolecular interaction, Studying Antimicrobial Drug Resistance, targeting enzyme beta-lactamase & folate biosynthesis pathway, |
|
Naveen Kumar |
IIT ROORKEE |
BIOMED |
Molecular Biology, Synthetic Biology, Gene regulation, Microbial Biotechnology and Nanobiotechnology, Aptamers and MEMS nanodevices in Diagnostics, Probiotic recombinant enzymes, NanoBiotic Materials, Microbes' mediated bioremediation of polluted environments., Isolation and characterization of microbes from extreme and polluted environments. , |
|
Pravindra Kumar |
IIT ROORKEE |
BIOMED |
Infectious disease and therapeutics, Plasticizers biodegradation, Crystallography and Bioinformatics, Use of structural biology to develop novel biocatalysts and therapeutics, |
|
Prabhat Kumar Mandal |
IIT ROORKEE |
BIOMED |
Cancer Biology, L1 retrotransposon activity in oral cancer, Human Genetics, Jumping genes in health and disease, Diagnosis, Generation of inhouse polyclonal and monoclonal antibody, cancer diagnosis kit, |
|
Prasenjit Mondal |
IIT ROORKEE |
BIOMED |
Energy and environmental engineering, Water treatment, energy from biomass & wastes, separation processes, LCA, waste plastics management, |
|
Maya S. Nair |
IIT ROORKEE |
BIOMED |
Biophysics, Structural Biology, NMR and other spectroscopic techniques, Biomlecular interactions usingspectroscopic techniques and NMR, Biophysics, Structural Biology, NMR and other spectroscopic techniques, DNA-ligand interaction, Protein structure, protein -DNA interaction, Biophysics, Structural Biology, NMR and other spectroscopic techniques, Natural product isolation, characterization, biosynthesis of nanoparticles, |
|
Sulakshana P.Mukherjee |
IIT ROORKEE |
BIOMED |
Structural and Molecular Biology: Protein-protein, Protein-DNA interaction, :-------using NMR, various biophysical and biochemical methods, |
|
Gopinath Packirisamy |
IIT ROORKEE |
BIOMED |
Biomedical nanotechnology, Drug delivery, Bioimaging , Tissue engineering, |
|
Ranjana Pathania |
IIT ROORKEE |
BIOMED |
Antibiotic Resistance, Bacterial Pathogenesis, Small RNA in Acinetobacter baumannii, Chemical genetic approaches for antibacterial drug discovery, |
|
Krishna Mohan Poluri |
IIT ROORKEE |
BIOMED |
Biomolecular NMR Spectroscopy, Molecular Biophysics, Structural Biology, Biophysical Chemistry, Protein Evolution-Structure-Stability-Dynamics-Function Paradigm, Biomolecular Interactions, Structure based Drug Design, Structural Immunology, Glycobiology, Structural Virology, Protein Folding, |
|
R. Prasad |
IIT ROORKEE |
BIOMED |
Molecular Biology, Infectious diseases, Genomics & Proteomics of Fungal Biofilm; MDR, anti-biofilm agents, drug discovery,Immunodominat antigens for diagnostic and vaccine , Molecular study of Abiotic Stress: expression and characterization of genes involved , in osmotic stress & anti-oxidative enzymes from plants, functional validation by RNAi technnolgy, Bio-therapeutics and Bio-Pharmaceutics: antimicrobial, anti-oxidative and immuno-modulatory , molecules from plants,coated nano-particles development & evaluation in vitro & in vivo assays. , |
|
Soma Rohatgi |
IIT ROORKEE |
BIOMED |
Infectious Disease Immunology, Vaccine Development and Research, Antibody Therapeutics, Monoclonal Antibodies, Antibody Engineering, Molecular Biology and Immunogenetics, VDJ rearrangements at Single cell level, Antibody Repertoire studies, Immunomodulation, Clinical and Translational Immunology, Human case/control studies in the setting of Infectious Diseases (fungal and viral pathogens), Biomarker Analysis, |
|
Partha Roy |
IIT ROORKEE |
BIOMED |
Animal Biotechnology, Molecular Endocrinology, Mechanism of hormone actions, Stem Cell Biology, Cancer Biology and therapeutics, Tissue Engineering, |
|
Pranita P. Sarangi |
IIT ROORKEE |
BIOMED |
Cellular and Molecular Immunology, Immunopathology of infectious and inflammatory diseases, Immunooncology, Cancer Immunoediting, Immunomodulatory therapeutics, Systems Immunology, |
|
A.K. Sharma |
IIT ROORKEE |
BIOMED |
Biochemistry, Biophysics, Macromolecular crystallography, Protein biochemestry and structural biology, |
|
Deepak Sharma |
IIT ROORKEE |
BIOMED |
Computational Biology, Translational Bioinformatics, Medicoinformatics, Machine Learning, Systems Biology, Pathways/Networks, Motifs, Flaviviruses, Mycobacteria, Metagenomics, |
|
R.P. Singh |
IIT ROORKEE |
BIOMED |
Microbial Biotechnology, Nanobiotechnology, Microbial Enzymes, Molecular Biology, Biofuels, Bioremediation, Drug Delivery Systems, |
|
Jitin Singla |
IIT ROORKEE |
BIOMED |
Computational analysis of Cryo-electron tomograms and Soft X-ray tomograms, Computational Biology, ArtScience, Machine Learning, Computational Structural Biology, |
|
Debabrata Sircar |
IIT ROORKEE |
BIOMED |
ROS-omics: Comprehensive omics of apples and pear, Use of genomics & metabolomics resources for the improvement of fruit quality of Rosaceous plant, Metabolic Pathway Engineering using SMART Plant cells, Engineering of secondary metabolic pathways in selected cis genically modified medicinal plants, Non-invasive Sensors for plant quality monitoring, Prediction of fruit quality using non-invasive metabolite-based electronic sensors , Non-invasive
sensors for plant disease detection, Detection of rice blast and apple disease using SMART sensor, Plant metabolomics, Mass spectrometry based plant metabolomics: medicinal and fruit plants, Non-invasie mobile phone based sensor, Portable sensor for quantification of natural products from medicinal plants, |
|
Shailly Tomar |
IIT ROORKEE |
BIOMED |
Antiviral research , Discovery of structure based antivirals against RNA arboviruses (Chikungunya), Molecular and Structural Virology, Structural studies (X-ray and Cryo Electron microscopy (CryoEM) of pathogenic virus/viral proteins , Molecular diagnostics , Molecular diagnosis of infectious viral diseases epidemic in India and Indian subcontinent , Systems Virology:, Alphaviruses and Flaviviruses , |
|
Shri Ram Yadav |
IIT ROORKEE |
BIOMED |
Plant Developmental Biology; Functional genomics of plant root organogenesis; Cell fate determination and tissue trans-differentiation; Epigenetic control of gene expression, |
|
Dr Anamika Bhargava |
IIT Hyderabad |
Biotechnology |
Electrophysiology, Ion channel function in heath and disease, Channelopathies, voltage gated calcium channels as drug targets, Zebrafish as an animal model. Drug screening/toxicity studies using zebrafish, Molecular mechanism of diseases in zebrafish |
|
Dr Rajakumara Eerappa |
IIT Hyderabad |
Biotechnology |
Structural Biology, X-ray Crystallography, Epigenetic and DNA repair, Protein/enzyme engineering for application in organic or pharmaceutical industry and Structure based drug design. |
|
Dr. Gunjan Mehta |
IIT Hyderabad |
Biotechnology |
Chromosome Biology and Cell Division, Transcription Regulation, Single-Molecule Imaging and Fluorescence Microscopy, Epigenetic Transcription Memory/Mitotic Bookmarking, Developmental Disorders and Cancers |
|
Dr Ashish Misra |
IIT Hyderabad |
Biotechnology |
RNA biology, Genomics and transcriptomics |
|
Dr Basant Kumar Patel |
IIT Hyderabad |
Biotechnology |
Molecular Biology of Prion and Amyloid diseases, Yeast Saccharomyces cerevisiae genetics, Bio-chemistry and bio-physics of protein misfolding. |
|
Dr N. K. Raghavendra |
IIT Hyderabad |
Biotechnology |
Innate Immunity, cancer, HIV. |
|
Dr Thenmalarchelvi Rathinavelan |
IIT Hyderabad |
Biotechnology |
Bacterial glycobiology, Transition state structures of proteins, DNA ...protein interaction, DNA structure and dynamics. |
|
Dr Sandipan Ray |
IIT Hyderabad |
Biotechnology |
Circadian clocks and sleep, Host and parasite circadian rhythms in infectious diseases, Mechanism of pharmacological modulators of circadian clocks, Systems biology, Clinical proteomics and mass spectrometry |
|
Dr Anindya Roy |
IIT Hyderabad |
Biotechnology |
Molecular and cellular biology of DNA damage, recognition, and repair. |
|
Agneyo Ganguly |
IIT KHARAGPUR |
BIOTECH |
Mechanistic studies of RecQ helicases
Protein protein interactions |
|
Amit Kumar Das |
IIT KHARAGPUR |
BIOTECH |
Structural Biology
Macromolecular X-ray Crystallography
Biochemistry and Biophysics
Structure based inhibitor design
Bioinformatics |
|
Ananta Kumar Ghosh |
IIT KHARAGPUR |
BIOTECH |
Recombinant DNA Technology
Immunotechnology
Antimicrobial peptides
Virology
Mycotoxin |
|
Anindya Sundar Ghosh |
IIT KHARAGPUR |
BIOTECH |
Bacterial biofilm formation
Antibiotic Resistance mechanisms
Penicillin-interactive enzymes
Multi-drug resistance efflux pumps
Bacterial cell shape |
|
Mrinal Kumar Maiti |
IIT KHARAGPUR |
BIOTECH |
Plant Molecular Biology
Functional Genomics of Rice Crop
Biotechnology of Plants, Fungi and Algae
Lipid Metabolic Engineering
Bioprospecting of Endophytic Microbes |
|
Pinaki Sar |
IIT KHARAGPUR |
BIOTECH |
Microbial genomics and metagenomics
Microbiology of deep biosphere
Bioremediation and Biodegradation
Geomicrobiology, Astrobiology
Bioremediation, CO2 sequestration |
|
Ramkrishna Sen |
IIT KHARAGPUR |
BIOTECH |
Bioprocess Engineering and Technology
Biorefinery for Biofuels and Renewables
CO2 Utilization and Waste Valorization
Environmental and Marine Biotechnology
Green Surfactants and Polymers |
|
Ranjit Prasad Bahadur |
IIT KHARAGPUR |
BIOTECH |
Bioinformatics and Computational Biology
Big-Data Bioanalytics |
|
Riddhiman Dhar |
IIT KHARAGPUR |
BIOTECH |
Genotype-phenotype mapping
Phenotypic heterogeneity
Drug resistance evolution |
|
Satyahari Dey |
IIT KHARAGPUR |
BIOTECH |
Prebiotics nutraceuticals: rice/millets
Probiotics nutraceuticals: Lactobacilli
Immunostimulating molecules: beta glycan
Microbial consortia: root moisturizer
Proven technologies to Atmanirbharata |
|
Somdeb Bose Dasgupta |
IIT KHARAGPUR |
BIOTECH |
Host-Parasite interaction
Host-directed Therapeutics
Novel Microbial Drug targets
Point-of-Care Diagnostics
Microbial pathogenesis |
|
Sudip Kumar Ghosh |
IIT KHARAGPUR |
BIOTECH |
Plant Molecular Biology
nanobiotechnology
Molecular Cell biology of Parasite |
|
Dr. Dhiraj Bhatia |
IIT GANDHINAGAR |
BIOTECH |
Cellular and Molecular Bioengineering apply engineering approaches to understand quantitatively fundamental cellular functions, and to explore this understanding for designing improved technologies. We use Structural DNA Nanotechnology to explore important aspects of receptor-mediated regulation of cell behavioural properties like endocytosis, signalling, migration and differentiation. The central paradigm of my research is developing DNA based nanodevices to probe, program and reprogram receptors mediated regulation of cellular functions and to achieve this, we explore techniques of biochemistry, molecular biology and cell biology to program parameters characterizing receptor-ligand properties in in-vitro and in cellular systems. Our research questions are inspired by health-care technologies of interest to pharmaceutical, biomedical and biotechnological companies, and we strongly invest in multi-disciplinary collaborative interactions, involving colleagues from both academics and industry. |
|
Dr. Ashutosh Srivastava |
IIT GANDHINAGAR |
BIOTECH |
Integrative modeling of macromolecular complexes.
Network analysis of protein structures.
Dynamics driven drug discovery.
Modeling and conformational analysis of disordered regions. |
|
Dr. Vijay Thiruvenkatam |
IIT GANDHINAGAR |
BIOTECH |
Vijay’s scientific career started as a small molecule crystallographer. Because of his aspiration to work in the field of macromolecular crystallography to study molecular mechanisms and functions in living cells, he went
on to do protein crystallography. Vijay’s current research focuses on X-ray crystallography of small molecules and macromolecules, which includes analysis of intra and intermolecular interactions, conformational changes, polymorphism, charge density analysis in organic, organo-metallic, inorganic compounds, dipeptides and proteins. One of his major expertise is in in-situ cryo-crystallization for the study of the crystal structure of liquids that crystallize at very low temperature and remain liquid at room temperature. |
|
Dr. Sharmistha Majumdar |
IIT GANDHINAGAR |
BIOTECH |
Transposons or mobile genetic elements which can jump from one place to another in the genome have been found in most living organisms, constitute large portions of many eukaryotic genomes, and have profound effects on gene
expression and genome evolution. The long-term goal of Sharmistha Majumdar’s research is to elucidate the evolution of transposable elements by investigating the mechanism of transposition and its control as well as the possible modification of these functions in specific mobile elements and their derivatives. |
|
Dr. Karla P. Mercado-Shekhar |
IIT GANDHINAGAR |
BIOTECH |
Ultrasound imaging and Tissue Characterization
Tissue elasticity imaging
Shear wave imaging
Quantitative ultrasound techniques
High-frequency ultrasound imaging
Tissue characterization |
|
Dr. Umashankar Singh |
IIT GANDHINAGAR |
BIOTECH |
Umashankar Singh’s lab is involved in identifying novel non-oncogene addiction mechanisms. His recent work has established the human factor CGGBP1 and interacting proteins as a paradigm to study non-canonical cell survival mechanisms that are advantageous for normal cell survival but absolutely indispensable for cancer cell proliferation. He employs epigenomic, genomic, transcriptomic and cDNA library-based proteome-wide studies in conjunction with cellular phenotyping. By enhancing our understanding of cell survival biology, his work potentially adds to the development of novel therapeutic modalities against survival vulnerabilities of cancer cells. |
|
Dr. Sharad Gupta |
IIT GANDHINAGAR |
BIOTECH |
Protein misfolding is one of the key events in the pathogenesis of neurodegenerative disorders including Alzheimer's Disease. Sharad Gupta's lab is trying to decode the underlying mechanism of protein misfolding and finding
ways to disrupt ensuing aggregation pathways. One major research focus is to identify tau aggregation inhibitors including peptides, short molecules or natural products. Along the way, his research group continues to develop methods for difficult peptide syntheses, controlled post-translational modification of proteins and new tools to detect various states of aggregation. |
|
Dr . Pratik Mutha |
IIT GANDHINAGAR |
BIOTECH |
The broad aim of Pratik Mutha’s research is to understand the principles and brain mechanisms that mediate the control of our actions, and to decipher how this control breaks down in case of damage to the brain. His research informs the development and advancement of rehabilitation strategies that improve motor function after neurological damage. His work thus contributes not just from a basic science perspective, but also from a translational standpoint. |
|
Dr. Bhaskar Datta |
IIT GANDHINAGAR |
BIOTECH |
Work in Bhaskar Datta's research laboratory is spans the following two broad themes: (a) Recognition of biomolecular targets by small molecules, (b) Development of nanobiocatalysts for environmental applications. His research in these areas is placed in the context of developing diagnostic and therapeutic tools for clinically and environmentally relevant subjects. |
|
Dr. Subramanian Sankaranarayanan |
IIT GANDHINAGAR |
BIOTECH |
Plant Developmental Biology
Biotechnology
Genetics
Molecular Biology
Cell Biology |
|
Dr. Atanu Kumar Metya |
IIT Patna |
Chemical and Biochemical Eng. |
Thermodynamics and statistical mechanics; Simulations: phase equilibria and nucleation; design of anti-icing surfaces, wetting phenomena; Structure, dynamics, and interfacial properties of solutions in bulk and confined systems; and force filed development using density functional theory. |
|
Dr. Sujoy Kumar Samanta |
IIT Patna |
Chemical and Biochemical Eng. |
Advanced Oxidation Processes, Wastewater Treatment, Photocatalysis, Microwave-Assisted Material Processing, Process Modeling and Simulation, Chemical Reaction Engineering, Renewable Energy, Biomass Gasification. |
|
Dr. Prolay Das |
IIT Patna |
Chemical and Biochemical Eng. |
DNA self assembly for production of 3-dimensional functional Nanostructures.
Clustered DNA damage and DNA repair mechanism in Nucleosome core particles. |
|
Dr. Nitin Dutt Chaturvedi |
IIT Patna |
Chemical and Biochemical Eng. |
Modeling and Simulation of Chemical processes Process system engineering Process Integration Pinch Analysis Industrial Energy Conservation Scheduling and optimization of batch processes |
|
Dr. Sandip Khan |
IIT Patna |
Chemical and Biochemical Eng. |
Molecular Modelling and Simulation, Statistical Thermodynamics, Equilibrium, Dynamic and Interfacial Properties of Complex fluids, Development of Novel Materials like super-hydrophobic, super-oleophobic, anti-fouling, anti-icing surfaces etc.; Self-Assembled Monolayer in application of chemical sensor, Thermo-physical properties of actinides compounds in application of nuclear fuel. |
|
Dr. Sushant Kumar |
IIT Patna |
Chemical and Biochemical Eng. |
Clean Hydrogen Production Methods, Hydrogen Storage using metal hydrides, CO2 Utilization and Capture, Catalysts for clean energy applications. |
|
Dr. Anoop Kumar Gupta |
IIT Patna |
Chemical and Biochemical Eng. |
Computational fluid dynamics Non-Newtonian flow rheology Motion of bubble/drops Particle dynamics in multiphase flows CFD-DEM coupled simulations Heat transfer in Nanofluids Modelling of Phase change materials |
|
A. B. Kunnumakkara |
IIT GUWHATI |
BIOTECH |
Role of inflammatory pathways in cancer development, Identification of novel biomarkers for cancer diagnosis and prognosis, Cancer drug discovery, Development of transgenic and gene knockout mouse models for biomedical research |
|
Aiyagari Ramesh |
IIT GUWHATI |
BIOTECH |
Nanobiotechnology, Chemistry-Biology Interface for Developing Antibacterials and Sensors |
|
Arun Goyal |
IIT GUWHATI |
BIOTECH |
Molecular Biology, Protein Engineering, Structural and Functional Proteomics of Carbohydrate active enzymes and other industrially important microbial enzymes |
|
Biman B Mandal |
IIT GUWHATI |
BIOTECH |
Cell based tissue engineering, Biomaterials,Stem cells, Drug delivery systems |
|
Debasish Das |
IIT GUWHATI |
BIOTECH |
Metabolic engineering, Biochemical engineering,Modelling of fermentation process, Biofuel |
|
Gurvinder Kaur Saini |
IIT GUWHATI |
BIOTECH |
Fungal Biotechnology, Biological Control, DNA fingerprinting and Transformation studies, Studies on extracellular enzymes and toxic metabolite production, Development of a potent biopesticide. |
|
Kannan Pakshirajan |
IIT GUWHATI |
BIOTECH |
Environmental Technology |
|
Latha Rangan |
IIT GUWHATI |
BIOTECH |
Applied Biodiversity. |
|
Lingaraj Sahoo |
IIT GUWHATI |
BIOTECH |
Genetic engineering and functional genomics of plants. |
|
Pranab Goswami |
IIT GUWHATI |
BIOTECH |
Biosensors and Biofuel cells |
|
Rajaram Swaminathan |
IIT GUWHATI |
BIOTECH |
A. Biophotonics B. Protein Structure and Dynamics C. Proteome Analysis D. Consequences of molecular crowding inside living cells |
|
Rakhi Chaturvedi |
IIT GUWHATI |
BIOTECH |
Plant Tissue Culture & Secondary Metabolite Production |
|
Ranjan Tamuli |
IIT GUWHATI |
BIOTECH |
Calcium signaling, Genetics, DNA repair |
|
Sanjukta Patra |
IIT GUWHATI |
BIOTECH |
Enzyme and Microbial Technology |
|
Siddhartha S. Ghosh |
IIT GUWHATI |
BIOTECH |
Cancer Therapeutics, Nanotheranostics, Exploring New Areas such as, EMT dynamics in microfluidics, Exosomes and Notch signaling in cancer |
|
Utpal Bora |
IIT GUWHATI |
BIOTECH |
Biomedical Engineering, Biodiversity and Bio-entrepreneurship |
|
V. Venkata Dasu |
IIT GUWHATI |
BIOTECH |
Bioprocess Development, Metabolic Engineering |
|
Vibin Ramakrishnan |
IIT GUWHATI |
BIOTECH |
Computational Biology, Bioinformatics, Biophysics, Bio-Organic Chemistry, Bio-nanotechnology |
|
Vishal Trivedi |
IIT GUWHATI |
BIOTECH |
Intracellular Signaling in Plasmodium falciparum |
|
Anil Mukund Limaye |
IIT GUWHATI |
BIOTECH |
Hormonal regulation of gene expression |
|
B Anand |
IIT GUWHATI |
BIOTECH |
Structural Biology, Bioinformatics & Computational Biology, RNA Biology, Molecular Evolution and Synthetic Biology |
|
Biplab Bose |
IIT GUWHATI |
BIOTECH |
NA |
|
Bithiah G. Jaganathan |
IIT GUWHATI |
BIOTECH |
Stem Cell Biology, Cancer signaling |
|
Lalit Mohan Pandey |
IIT GUWHATI |
BIOTECH |
Surface and interfacial science particularly in Bio-interfaces and Biomaterials, Environmental Biotechnology |
|
Manish Kumar |
IIT GUWHATI |
BIOTECH |
Molecular interaction of host-pathogen-vector of infectious diseases |
|
Nitin Chaudhary |
IIT GUWHATI |
BIOTECH |
Peptide self-assembly and amyloid aggregates, Peptide-membrane interactions Curvature inducing proteins |
|
S Senthilkumar |
IIT GUWHATI |
BIOTECH |
Biocalorimetry, BioPAT, Real-time monitoring and control of bioprocess systems |
|
Sachin Kumar |
IIT GUWHATI |
BIOTECH |
Molecular biology of paramyxoviruses |
|
Shankar Prasad Kanaujia |
IIT GUWHATI |
BIOTECH |
Structural Biology and Bioinformatics Studies |
|
Soumen Kumar Maiti |
IIT GUWHATI |
BIOTECH |
Biochemical Engineering, Biofuel, Bioprocess modeling, control, optimization, Metabolic engineering, Downstream processing, Membrane separation, Bioremediation |
|
Kusum K Singh |
IIT GUWHATI |
BIOTECH |
Post-transcriptional gene regulation by RNA binding Proteins |
|
Navin Gupta |
IIT GUWHATI |
BIOTECH |
Imaging Genetics, Biomedical Signal/Image Processing, Multimodal Analysis, Computer Aided Diagnosis, Biomedical Instrumentation |
|
Pranjal Chandra |
IIT GUWHATI |
BIOTECH |
Clinical Diagnostics (Cancer cells, DNA, RNA, bio-markers), Nano-biosensors (Aptamer, antibody, enzyme) based biological phenomenon investigation, Porous silicon based label free self reporting optical nanosensors, Microfluidics and Nanomachines. |
|
Priyadarshi Satpati |
IIT GUWHATI |
BIOTECH |
Molecular dynamics (MD) simulation, Electronic Structure calculations of small molecules |
|
Rajkumar P. Thummer |
IIT GUWHATI |
BIOTECH |
Stem Cell Engineering and Regenerative Medicine |
|
Selvaraju Narayanasamy |
IIT GUWHATI |
BIOTECH |
Environmental Biotechnology, Bioprocess Engineering, Biochemical Engineering |
|
Shirisha Nagot |
IIT GUWHATI |
BIOTECH |
Organelle biology and Inter-organelle communication, Cellular Ageing, Membrane fission and fusion |
|
Souptick Chanda |
IIT GUWHATI |
BIOTECH |
Biomechanics, implant design and optimization, surgical simulations and soft computing |
|
Dr. Durba Pal |
IIT ROPAR |
BIOTECH |
Tissue engineering and Regenerative Medicine; Cell based therapeutics in disease biology |
|
Dr. Javed N. Agrewala |
IIT ROPAR |
BIOTECH |
Immunology of Infectious Diseases, Vaccines, and Gut Microbiome |
|
Dr. Bodhisatwa Das |
IIT ROPAR |
BIOTECH |
Biomaterials, Tissue Engineering, Nanomedicine, Wound Healing |
|
Dr. Navin Kumar |
IIT ROPAR |
BIOTECH |
Biomaterials, Biological and Biomaterial Characterization, Biomechanics, Mechanics of Nanomaterials, Finite Element Modeling (FEM), Biomedical Engineering, Biomedical Instrumentation, and Bioimplants |
|
Dr. Kailash Chandra Jena |
IIT ROPAR |
BIOTECH |
Interfacial water structure, protein folding, soft matter interfaces, and colloids and model membrane systems |
|
Dr. P. Goyal |
IIT ROPAR |
BIOTECH |
Image Processing, Healthcare Apps and Analytics, Medical Imaging |
|
Dr. Ramjee Repaka |
IIT ROPAR |
BIOTECH |
Heat Transfer; Thermal Engineering |
|
Dr. Srivatsava Naidu |
IIT ROPAR |
BIOTECH |
Therapeutic targeting of basal transcriptional machinery; Non-coding RNA as cancer therapeutics |
|
Dr. Ashish K Sahani |
IIT ROPAR |
BIOTECH |
Instrumentation, Signal Processing and AI |
|
Dr. Rajesh Kumar |
IIT ROPAR |
BIOTECH |
Biomedical-Photonics, Microscopy Imaging, Spectroscopy, Physics in Medicine, (Healthcare, Food and Agriculture) |
|
Dr. Narinder Singh |
IIT ROPAR |
BIOTECH |
NA |
|
Dr. Deepti R Bathula |
IIT ROPAR |
BIOTECH |
Medical Image Processing and Analyses; Pattern recognition; Machine Learning and Computer Vision |
|
Dr. Yashveer Singh |
IIT ROPAR |
BIOTECH |
Polymeric biomaterials for drug delivery and tissue engineering applications |
|
Dr. Jitendra Prasad |
IIT ROPAR |
BIOTECH |
Biomechanics, Bone Fracture Healing, Mechanotransduction, Structural and Multidisciplinary Design Optimization, Computational Mechanics, and Agent Based Modelling |
|
Dr. Amit Kumar |
IIT INDORE |
BIOTECH |
Molecular Structural Biology
NMR Spectroscopy
Target Identification and Drug discovery for different diseases |
|
Dr. Debasis Nayak |
IIT INDORE |
BIOTECH |
Viral Nanotechnology: Vesicular stomatitis virus glycoprotein based virus-like particles (VLPs) platform for targeted drug delivery
Viral vector vaccines: Recombinant VSV (rVSV) based multi-valent vaccine development
Emerging viral infection of the CNS: Immunopathogenesis of encephalitis and meningitis caused by emerging neuroviruses (CHIKV, DENV) |
|
Dr. Prashant Kodgire |
IIT INDORE |
BIOTECH |
Molecular Biology
Molecular Immunology |
|
Dr. Sharad Gupta |
IIT INDORE |
BIOTECH |
Non-Invasive Characterization and Disease Diagnosis |
|
Dr. Kiran Bala |
IIT INDORE |
BIOTECH |
Biodiesel Production
Carbon Sequestration
Bioremediation |
|
Dr. Mirza S. Baig |
IIT INDORE |
BIOTECH |
Cancer and Innate Immunity
Inflammation and cell signaling |
|
Dr. Hem C. Jha |
IIT INDORE |
BIOTECH |
Host-pathogen interaction- Epstein-Barr virus and Helicobacter pylori associated co-infection in cancer progression.
Epigenetic regulation- Pathogens derived pathogenesis in cancer.
Pathogens burden during viral infection of Gastric Cancer, Head and Neck Cancer and Multiple Sclerosis.
Drug discovery in cancer and infectious agents derived diseases.
Genetic Engineering |
|
Dr. Parimal Kar |
IIT INDORE |
BIOTECH |
Structure and dynamics of proteins and nucleic acids via multiscale coarse-grained/all-atom simulations
Molecular dynamics simulations of glycans and protein-glycan complexes
Multiscale modeling of biomolecular recognitions
Protein-membrane interactions via Molecular Dynamics simulations |
|
Dr. Abhijeet Joshi |
IIT INDORE |
BIOTECH |
Biosensors
Biomaterials
Drug Delivery
Diagnostics
Theranostics |
|
Dr. Avinash Sonawane |
IIT INDORE |
BIOTECH |
Role of Mycobacterium tuberculosis glycoproteins and glycolipoproteins in modulation of host immune responses
Epigenomics of stem cells during M. tuberculosis infection
Host antimicrobial peptides in anti-mycobacterial immunity
Drug delivery
Development of L-asparaginase based therapy for the treatment of primary and relapse acute lymphatic leukemia |
|
Dr. G. S. Murthy |
IIT INDORE |
BIOTECH |
Bioprocess development and scaleup for production of value added bioproducts and biofuels.
Biological and bioprocess modeling, control and multicriteria optimization.
Systems analysis using technoeconomic analysis, life cycle assessment and resource assessment.
Resilience and sustainability at the nexus of nutrient-energy-water-land.
|
|
Shankar Manoharan |
IIT Jodhpur |
Biotechnology |
Molecular Microbiology, Host-Microbe Interaction, Genomics and Metagenomics |
|
Amit Kumar Mishra |
IIT Jodhpur |
Biotechnology |
Cellular and Molecular Neuroscience, Cell Cycle Regulation and Cancer |
|
Indranil Banerjee |
IIT Jodhpur |
Biotechnology |
Tissue engineering; Regenerative medicine; Biomaterials; Theranostic systems; Biomicrofluidic |
|
Mitali Mukerji |
IIT Jodhpur |
Biotechnology |
Genomics, Human molecular genetics, functional genomics of Alu repeats, Ayurgenomics, genetics of rare diseases |
|
Neeraj Jain |
IIT Jodhpur |
Biotechnology |
Neuroscience/Mammalian Sensory and Motor Systems; Tactile Information Processing; Brain Plasticity; Spinal Cord Injuries; Brain-Computer Interface; Brain Networks |
|
Neha Jain |
IIT Jodhpur |
Biotechnology |
Amyloids, Biofilms, Neurodegeneration, Molecular Biophysics, Microbiology |
|
Pankaj Yadav |
IIT Jodhpur |
Biotechnology |
Statistical Genetics, Deep Learning, Big Data Analytics |
|
Priyanka Singh |
IIT Jodhpur |
Biotechnology |
Cellular & Molecular Biology |
|
Raviraj Vankayala |
IIT Jodhpur |
Biotechnology |
Nanobiotechnology; Biomaterials; Drug Delivery; Theranostics; Photomedicine |
|
Sucharita Dey |
IIT Jodhpur |
Biotechnology |
Principles of protein robustness to mutation, Functional role of protein quaternary structure in mutation and disease, Prediction of disease mutations, Identifying structural determinants of inter-subunit communication -- Allostery |
|
Sudipta Bhattacharyya |
IIT Jodhpur |
Biotechnology |
Structural Biology, Enzyme Chemistry, Protein Engineering |
|
Surajit Ghosh |
IIT Jodhpur |
Biotechnology |
Chemical Neurobiology, Chemical Biology and Cancer Biology |
|
Sushmita Jha |
IIT Jodhpur |
Biotechnology |
Cellular and Molecular Neuroscience, Cell and Molecular Physiology |
|
Sushmita Paul |
IIT Jodhpur |
Biotechnology |
Computational Biology and Bioinformatics |
|
Dr. Pradeep Srivastava |
IIT BHU |
Biochemical |
Microbial Engg., Bioreactor Kinetics, Modelling & Scaleup, Downstream Processing, Recombinant Proteins, Drug Delivery Techniqu, Tissue Engineering and IPR & Technology Transfer |
|
Dr. Vikash Kumar Dubey |
IIT BHU |
Biochemical |
Cell Death Pathways and Diseases; Protein Biochemistry; Protein Engineering, Biochemical Parasitology; Isolation and Purification of Commercially Important Enzymes |
|
Dr. Abha Mishra |
IIT BHU |
Biochemical |
Protein Chemistry, fermentation technology and Intellectual property rights (IPR). |
|
Dr. Vishal Mishra |
IIT BHU |
Biochemical |
Wastewater engineering, Bio-remediation and Food Technology |
|
Dr. Sanjay Kumar |
IIT BHU |
Biochemical |
Bioprocess development in biofuels and therapeutic protein, Biological analysis of water/wastewater |
|
Dr. Pranjal Chandra |
IIT BHU |
Biochemical |
Bio-Physio Sensors, Nanobioengineering, Microfluidics, Healthcare Technologies, Material Engineering for Diverse Applications |
|
Dr. Prodyut Dhar |
IIT BHU |
Biochemical |
Biomaterials, Biodegradable Polymers, Hybrid Proteins, Biopolymers & Bionanotechnology, Sustainable Energy Systems, Biorefinery, Cellulose & Renewable Materials |
|
Dr. Abhishek Suresh Dhoble |
IIT BHU |
Biochemical |
Microbiome Dynamics |
|
Dr. Neeraj Sharma |
IIT BHU |
BIOMED |
Bioinstrumentation, Biomedical Signal and image Processing. |
|
Dr. Ranjana Patnaik |
IIT BHU |
BIOMED |
Neurophysiology, Electrophysiology, Biomaterials, Biochemistry |
|
Dr. Nira Misra |
IIT BHU |
BIOMED |
BIomaterials, Nanocomposites |
|
Dr. Prasun Kumar Roy |
IIT BHU |
BIOMED |
Brain Research, Neuroscience, Neurotchnology, Medical Imaging (MRI, fMRI), Cognitive Processing |
|
Dr. Shiru Sharma |
IIT BHU |
BIOMED |
Biological control system, Mathematical modeling of biological system, Bio-instrumentation |
|
Dr. Sanjay Kumar Rai |
IIT BHU |
BIOMED |
Biomechanics |
|
Dr. Marshal |
IIT BHU |
BIOMED |
Biophyiscs, Biomaterials and Tissue Engineering, Stem Cell Reprogramming, Biosensors, Bio-MEMS, Nano-medicine, Plasma Physics |
|
Dr. Pradip Paik |
IIT BHU |
BIOMED |
Materials for Health Care and Therapeutic Applications: New designing and synthesis of Polymers, Ceramic, Composites, other Nanoscale Materials of Health care and Nanomedicine, in-plantable materials, Drug Delivery, Cancer Therapy, Nano vaccination, in-vitro and in-vivo studies |
|
Dr. Sanjeev Kumar Mahto |
IIT BHU |
BIOMED |
Cell and Tissue Engineering, Biofabrication, lab-on-a-chip, Neuroengineering |
|
Dr. A. R. Jac Fredo, Ph.D |
IIT BHU |
BIOMED |
Bio-Medical Signal and Image Processing, Bio-Medical Instrumentation, Computational Neuroscience, Developmental Psychology, Neuro-Informatics, Machine Learning, Composite Science |
|
Dr. Deepesh Kumar |
IIT BHU |
BIOMED |
NA |
|